Symantec Endpoint Protection has a tendency to preserve definitions that are no longer needed. I’ve written a powershell script in three variations.

First is a powershell script that deletes any folders in the Virusdef above the count of 3. So if there are 4 folders with definitions it will delete the oldest.

$Servers =@( Import-CSV ".\Server.csv")
Foreach ($Server in $Servers){$Folders =@( gci "\\$Server\C$\Program Files\Common Files\Symantec Shared\VirusDefs" | Where {$_.PsIsContainer -and $_.Name -notmatch "Binhub" -and $_.Name -notmatch "Texthub"} | Sort CreationTime -Descending | Select -Skip 3})
ForEach ($Folder in $Folders){Remove-Item $Folder -Force -Recurse}

Second is a powershell script that deletes any folder in de Virusdef folder older than 2 days ago. Of course only definition folders not the other two folders.

$Datum = (Get-Date).AddDays(-2)
$Servers = @(Import-CSV ".\Server.csv")
Foreach ($Server in $Servers){gci -Path "\\$Server\C$\Program Files\Common Files\Symantec Shared\VirusDefs" | Where-Object { $_.PSIsContainer -and $_.CreationTime -lt $Datum -and $_.Name -notmatch "Binhub" -and $_.Name -notmatch "Texthub" } | Remove-Item -Force}

The last script is a combination of the above. It will any folder older than two days ago skipping the first. If a server hasn’t updated its definition it will not delete the active  definition.

$Datum = (Get-Date).AddDays(-2)
$Servers = @(Import-CSV ".\Server.csv")
Foreach ($Server in $Servers){gci -Path "\\$Server\C$\Program Files\Common Files\Symantec Shared\VirusDefs" -Recurse -Force | Where-Object { $_.PSIsContainer -and $_.CreationTime -lt $Datum } | Sort CreationTime -Descending | Select -Skip 1| Remove-Item -Force}

All Script require a script.csv file with servers. Just a header with Server. Neighter do you need any delimiters. Just a list with servers

You can replace import-csv with get-content as needed.